Title: Lead Integration Engineer Location: Onsite, Pittsburgh, PA 15213 Type: Direct-Hire/Permanent Hours: Standard business hours Overview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the integration, optimization, and operation of complex fluidic and instrumentation systems for advanced human-relevant experimental platforms. This role focuses on system-level design and implementation of fluid handling architectures, ensuring reliable, reproducible, and physiologically relevant operation across single- and multi-component platforms. The position will contribute to development of robust, scalable systems that integrate mechanical, fluidic, and control elements to support standardized experimental workflows. Responsibilities: Design, develop, and optimize fluidic systems, including manifolds, tubing layouts, and pump-controlled flow networks Implement stable, leak-free circulation systems with controlled and reproducible flow profiles across experimental platforms Support development of physiologically relevant flow conditions, including continuous and directional flow regimes Integrate fluidic systems with broader experimental platforms, including device interfaces, instrumentation, and control systems Contribute to system-level architecture design, coordinating fluidic, mechanical, and sensing components Develop and implement control strategies for pumps, valves, and fluid routing systems Perform system testing, validation, and troubleshooting to ensure operational reliability and consistency Maintain detailed documentation of system configurations, standard operating procedures (SOPs), and performance validation Collaborate with multidisciplinary teams to align system functionality with experimental and operational requirements Contribute to improvement of system robustness, usability, and scalability for sustained and repeatable operation Requirements: Bachelor's degree in Mechanical Engineering, Electrical / Systems Engineering, or a related field Minimum of 3 years of relevant experience in fluid systems, instrumentation, or experimental platform development Experience with fluid handling systems, pumps, tubing, or flow control architectures Experience with system integration and hardware-based experimental platforms Strong analytical, troubleshooting, and problem-solving skills Ability to work effectively in multidisciplinary research and engineering environments Preferred Qualifications Master's or Ph.D. in a relevant engineering discipline Experience with microfluidics, perfusion systems, or biologically relevant flow systems Familiarity with control systems, sensors, and automated or semi-automated fluid handling platforms Experience with design and implementation of complex, multi-component systems Experience with data acquisition, monitoring systems, or system diagnostics Experience working at the interface of engineering and biological systems Experience in controlled or regulated laboratory environments #M3 #LI-MD2 Ref: #558-ScientificPDN-a22a4643-63fa-422a-bc15-7c06dc5087d9